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Dasatinib Impurity 8 (Dasatinib Dimeric Impurity)

Impurity

CAS Number

910297-61-9

Molecular Formula

C36H34Cl2N12O2S2

Product format

Neat

Molecular Weight

801.77

API Family

Dasatinib Monohydrate

Synonyms

2, 2'-((piperazine-1, 4-diylbis(2-methylpyrimidine-6 and 4-diyl))bis(azanediyl))bis(N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide)

Iupac Name

N-(2-chloro-6-methylphenyl)-2-[[6-[4-[6-[[5-[(2-chloro-6-methylphenyl)carbamoyl]-1, 3-thiazol-2-yl]amino]-2-methylpyrimidin-4-yl]piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1 and 3-thiazole-5-carboxamide

InChI

InChI=1S/C36H34Cl2N12O2S2/c1-19-7-5-9-23(37)31(19)47-33(51)25-17-39-35(53-25)45-27-15-29(43-21(3)41-27)49-11-13-50(14-12-49)30-16-28(42-22(4)44-30)46-36-40-18-26(54-36)34(52)48-32-20(2)8-6-10-24(32)38/h5-10,15-18H,11-14H2,1-4H3,(H,47,51)(H,48,52)(H,39,41,43,45)(H,40,42,44,46)

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COA COO

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Synthesis

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