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Azithromycin EP Impurity L (Azithromycin N-Oxide)

Impurity

CAS Number

90503-06-3

Molecular Formula

C38H72N2O13

Product format

Neat

Molecular Weight

764.98

USP Description

Azithromycin N-Oxide

Storage

-20°C

Shipping

Frozen (-20°C)

API Family

Azithromycin

Synonyms

Azithromycin N-Oxide, 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2, 6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy]-2-ethyl-3, 4, 10-trihydroxy-3, 5, 6, 8, 10, 12, 14-heptamethyl-11-[[3, 4, 6-trideoxy-3-(dimethyloxidoamino)-ß-D-xylo-hexopyranosyl]oxy]-, (2R, 3S, 4R, 5R, 8R, 10R, 11R, 12S, 13S, 14R)-, 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2, 6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy]-2-ethyl-3, 4, 10-trihydroxy-3, 5, 6, 8, 10, 12, 14-heptamethyl-11-[[3, 4, 6-trideoxy-3-(dimethylamino)-ß-D-xylo-hexopyranosyl]oxy]-, N-oxide, [2R-(2R*, 3S*, 4R*, 5R*, 8R*, 10R*, 11R*, 12S*, 13S*, 14R*)]-, 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2, 6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy]-2-ethyl-3, 4, 10-trihydroxy-3, 5, 6, 8, 10, 12, 14-heptamethyl-11-[[3, 4, 6-trideoxy-3-(dimethyloxidoamino)-ß-D-xylo-hexopyranosyl]oxy]-, [2R-(2R*, 3S*, 4R*, 5R*, 8R*, 10R*, 11R*, 12S*, 13S*, 14R*)]- and Azithromycin Impurity L

Smiles

CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)[N+](C)(C)[O-])[C@](C)(O)C[C@@H](C)CN(C)[C@H](C)[C@@H](O)[C@]1(C)O

Iupac Name

(2S,3R,4S,6R)-2-[[(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-1-oxa-6-azacyclopentadec-11-yl]oxy]-3-hydroxy-N,N,6-trimethyloxan-4-amine oxide


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Synthesis

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